12, Jayakumar
نویسندگان
چکیده
Ficus is a pan-tropical genus of trees, shrubs and vines occupying a wide variety of ecological niches; most are evergreen, but some deciduous species are endemic to areas outside of the tropics and to higher elevations. Healthy Wistar rats weighing between 180-220 g were used to carry out acute oral toxicity studies by the ‘staircase’ method. All successive extracts of Anjir leaves in 0.5% tween 80 was administered orally by gavages in graduated dose to several groups of experimental animals, one dose being used per group. The preliminary phytochemical screening like Saponins, Tannins, Amino acids, Proteins, Glycosides, Cardiac glycosides, Alkaloids, Carbohydrates and Flavonoids was done with the ethanolic extract of Anjir Leaves according to the procedure. The present study, diabetic rats had lower body weights, high blood glucose level as compared to the normal rats, which confirmed the induction of diabetic by alloxan. In spite of the increased food consumption, loss of body weight due to defect in glucose metabolism and excessive breakdown of tissue protein is a characteristic condition in diabetics. The treatment with ethanolic extract of Anjir leaves improved the average body weights of rats which indicate control over polyphagia and muscle wasting resulted due to hyperglycemic condition.
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